Hydrogen Sulfide-Preconditioned Mesenchymal Stem Cells Attenuate Ferroptosis in Corneal Alkali Burn via the AMPK/Nrf2/HO-1 Pathway in an IL-10-Dependent Manner
H2S preconditioning augmented the anti-inflammatory and anti-ferroptotic effects of MSCs via activation of the AMPK/Nrf2/HO-1 pathway in an IL-10-dependent way, offering a novel strategy for corneal alkali burn treatment.
Authors
- Yifei Huang (ORCID: https://orcid.org/0000-0002-7089-6426)
- Yilin Jiang (ORCID: https://orcid.org/0009-0000-2459-7663)
- Mingxiong Chen (ORCID: https://orcid.org/0000-0002-3239-8135)
- Haolan Qi (ORCID: https://orcid.org/0000-0002-3930-1228)
- Hanrui Yu (ORCID: https://orcid.org/0000-0002-0864-4359)
- Qun Wang (ORCID: https://orcid.org/0000-0003-4853-1727)
- Xiaoqi Li (ORCID: https://orcid.org/0000-0001-7200-2134)
- Junyi Wang (ORCID: https://orcid.org/0000-0003-3985-0822)
- Li Zhao (ORCID: https://orcid.org/0009-0006-0022-5973)
- An Wang
- Liqiang Wang
Institutions
- Nankai University (CN)
- Chinese General Hospital College of Nursing and Liberal Arts (PH)
- People's Liberation Army No. 150 Hospital (CN)
- Shandong Provincial Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Chinese People's Liberation Army (CN)
- Chinese People’s Liberation Army 263 hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1167/iovs.66.12.58
- Citations
- 1
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 1.11