Anesthetic Considerations for Cesarean Section in a Woman With Systemic Mastocytosis
Mastocystosis is a multisystem disorder characterized by mast cell deposition throughout internal organs. It can present in a similar fashion to anaphylaxis, with widespread mast cell degranulation triggered by a range of drugs, sleep deprivation, foods, and physical or emotional stress, such as pain or infection. We present a case of a woman in her 20s with her second pregnancy with suspected mastocytosis who required an elective cesarean section, and consider the implications of anesthetic management. A "recipe" with rationale has been devised to aid others who may come across a similar case in both the elective and emergency settings.
Authors
- Erica Jolly
- Lydia Richardson
- William R. Phipps
Institutions
- University Hospital Southampton NHS Foundation Trust (GB)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-21
- DOI
- https://doi.org/10.7759/cureus.92864
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00