A Rare Presentation of Posterior Reversible Encephalopathy Syndrome in a Previously Healthy Young Male: A Case Report

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by vasogenic cerebral edema, typically associated with hypertension, renal failure, or immunosuppressive therapy. We present a unique case of a 19-year-old, previously healthy male who developed PRES in the setting of an acute hypertensive crisis, with an atypical presentation including severe cerebellar edema and obstructive hydrocephalus, necessitating emergent neurosurgical intervention. Unlike typical cases, this patient had no prior history of hypertension or known risk factors, highlighting the importance of considering secondary causes of hypertension in young individuals. His hospital course was further complicated by visual impairment due to hypertensive retinopathy and pneumonia, requiring bilevel positive airway pressure (BiPAP) support. This case expands the spectrum of PRES presentations, emphasizing that acute, severe hypertension alone can precipitate life-threatening complications. Early recognition, aggressive blood pressure management, and thorough evaluation for underlying etiologies are crucial in optimizing patient outcomes.

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Publication Details

Journal
Cureus
Published
2025-09-21
DOI
https://doi.org/10.7759/cureus.92870
Primary Topic
Neurological Complications and Syndromes
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Presentation of Posterior Reversible Encephalopathy Syndrome in a Previously Healthy Young Male: A Case Report

Matthew Jordan, Jatin Goyal, Morgan McMasters, Rushil Randive
Cureus
Neurological Complications and Syndromes
article

A Rare Presentation of Posterior Reversible Encephalopathy Syndrome in a Previously Healthy Young Male: A Case Report

Matthew Jordan, Jatin Goyal, Morgan McMasters, Rushil Randive
article en

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by vasogenic cerebral edema, typically associated with hypertension, renal failure, or immunosuppressive therapy. We present a unique case of a 19-year-old, previously healthy male who developed PRES in the setting of an acute hypertensive crisis, with an atypical presentation including severe cerebellar edema and obstructive hydrocephalus, necessitating emergent neurosurgical intervention. Unlike typical cases, this patient had no prior history of hypertension or known risk factors, highlighting the importance of considering secondary causes of hypertension in young individuals. His hospital course was further complicated by visual impairment due to hypertensive retinopathy and pneumonia, requiring bilevel positive airway pressure (BiPAP) support. This case expands the spectrum of PRES presentations, emphasizing that acute, severe hypertension alone can precipitate life-threatening complications. Early recognition, aggressive blood pressure management, and thorough evaluation for underlying etiologies are crucial in optimizing patient outcomes.

CureusVol. 17(9)
Florida International University (US), Baptist Health South Florida (US)
Openalex Percentile: Top 69%
Neurological Complications and Syndromes
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