Identification of peripheral biomarkers through metabolomic analysis in patients with bipolar disorder treated with mood stabilizers: an exploratory study
The findings from this exploratory study suggest that patients treated with lithium show distinctive metabolomic biosignatures, specifically pointing to energy metabolism and mitochondria functioning, thus potentially suggesting possible biosignatures of mood-stabilizing treatments.
Authors
- Caterina Chillotti (ORCID: https://orcid.org/0000-0002-8581-9407)
- Luigi Atzori (ORCID: https://orcid.org/0000-0003-1350-3574)
- Aldo Manzin (ORCID: https://orcid.org/0000-0003-2961-3428)
- Martina Spada (ORCID: https://orcid.org/0009-0003-9592-1178)
- Bernardo Carpiniello (ORCID: https://orcid.org/0000-0002-5385-7871)
- Marco Pinna
- Donatella Congiu
- Alessio Squassina (ORCID: https://orcid.org/0000-0001-7415-7607)
- Mirko Manchia (ORCID: https://orcid.org/0000-0003-4175-6413)
- Maria Del Zompo (ORCID: https://orcid.org/0000-0001-9491-5938)
- Pasquale Paribello (ORCID: https://orcid.org/0000-0001-9953-6929)
- Giovanni Severino (ORCID: https://orcid.org/0000-0002-6354-2662)
- Claudia Pisanu (ORCID: https://orcid.org/0000-0002-9151-4319)
- Raffaella Ardau (ORCID: https://orcid.org/0000-0002-6420-5158)
- Martina Contu (ORCID: https://orcid.org/0009-0009-7549-8070)
- Cristina Piras (ORCID: https://orcid.org/0000-0003-0750-4837)
- Vanessa Palmas (ORCID: https://orcid.org/0009-0001-8961-2198)
- Anna Meloni
- Federico Suprani
Institutions
- Dalhousie University (CA)
- University of Cagliari (IT)
Publication Details
- Journal
- The International Journal of Neuropsychopharmacology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1093/ijnp/pyaf071
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondazione di Sardegna