Indole ring expansion into quinolines with TMSCCl<sub>3</sub>/TMSCBr<sub>3</sub>
Reactivity adaptation speciation perceives reactants as a dynamic supply pool of shifting reactive units for opportunistic reactivity-matching diverse-manifold pathways to varied reactivity patterns, revealing the title C2C3-CCl/CBr insertion ring expansion of indole into quinoline, N1-H-TMS nucleophilic substitution, and N1-H-CCl<sub>3</sub> nucleophilic substitution for the indole-TMSCCl<sub>3</sub>/TMSCBr<sub>3</sub> reactions.
Authors
- Hanxiao Xu (ORCID: https://orcid.org/0000-0001-9494-6216)
- Zhixin Wang (ORCID: https://orcid.org/0000-0001-5530-5344)
- Xuanzhen Han
- Jin Zhu (ORCID: https://orcid.org/0000-0003-4681-7895)
Institutions
- Nanjing University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04994f
- Citations
- 1
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.94