Environmental, Psychiatric, and Genetic Predictors of Alcohol Use Disorder Criterion Count: Analyses of African and European Ancestries
In both African and European ancestry groups, environmental factors explained the majority of the variance in AUD criterion count, but polygenic risk was also a statistically significant predictor. These findings may help inform clinical, research, and policy efforts to mitigate AUD risk.
Authors
- Peter J. Na (ORCID: https://orcid.org/0000-0003-3895-7417)
- Daniel Levey
- Joel Gelernter (ORCID: https://orcid.org/0000-0002-4067-1859)
- Rachel L. Kember (ORCID: https://orcid.org/0000-0001-8820-2659)
- Joseph D. Deak (ORCID: https://orcid.org/0000-0002-0540-6080)
- Robert H. Pietrzak (ORCID: https://orcid.org/0000-0002-5561-6414)
- Henry R. Kranzler
Institutions
- Yale University (US)
- VA Connecticut Healthcare System (US)
- National Center for PTSD (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- American Journal of Psychiatry
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1176/appi.ajp.20240893
- Citations
- 2
- Primary Topic
- Substance Abuse Treatment and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.71