Photodynamic therapy: prospects and application in the prevention of dental diseases (a review)

Photodynamic therapy is a rapidly developing non-invasive treatment method that holds significant promise in dental practice. This review article discusses the principles of action of photodynamic therapy, as well as the possibilities of its application in the prevention of dental diseases such as caries, periodontitis, peri-implantitis and oral tumors. The unique advantages of photodynamic therapy, such as selectivity of action, a broad spectrum of antimicrobial effects, the absence of resistance development and its synergistic effect with other treatment methods, are emphasized. However, challenges such as delivery of the photosensitizer, the penetration of light into deeper tissues, oxygen availability and the need for standardization of protocols are also recognized. The integration of advanced technologies such as nanotechnology and synthetic biology into photodynamic therapy may provide a solution to some of the current limitations of the method and further improve the effectiveness of photodynamic therapy in the prevention of dental diseases.

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Medical alphabet
Published
2025-09-24
DOI
https://doi.org/10.33667/2078-5631-2025-20-100-106
Primary Topic
Photodynamic Therapy Research Studies
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article
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article

Photodynamic therapy: prospects and application in the prevention of dental diseases (a review)

О. И. Ефимович, L. T. Mamedova, M. N. Podoinikova, Ekaterina Korosteleva
Medical alphabet
Photodynamic Therapy Research Studies
article

Photodynamic therapy: prospects and application in the prevention of dental diseases (a review)

О. И. Ефимович, L. T. Mamedova, M. N. Podoinikova, Ekaterina Korosteleva
article en

Abstract

Photodynamic therapy is a rapidly developing non-invasive treatment method that holds significant promise in dental practice. This review article discusses the principles of action of photodynamic therapy, as well as the possibilities of its application in the prevention of dental diseases such as caries, periodontitis, peri-implantitis and oral tumors. The unique advantages of photodynamic therapy, such as selectivity of action, a broad spectrum of antimicrobial effects, the absence of resistance development and its synergistic effect with other treatment methods, are emphasized. However, challenges such as delivery of the photosensitizer, the penetration of light into deeper tissues, oxygen availability and the need for standardization of protocols are also recognized. The integration of advanced technologies such as nanotechnology and synthetic biology into photodynamic therapy may provide a solution to some of the current limitations of the method and further improve the effectiveness of photodynamic therapy in the prevention of dental diseases.

Medical alphabet(20)
Moscow Regional Scientific Research Clinical Institute. MF Vladimirsky (RU), Regional Clinical Research (US)
Openalex Percentile: Top 63%
Photodynamic Therapy Research Studies
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Photodynamic therapy: prospects and application in the prevention of dental diseases (a review) — О. И. Ефимович, L. T. Mamedova, et al. · Medical alphabet (2025) | TGRS Research Map | TGRS