Plasma sphingolipids predict advanced liver fibrosis development in patients with type 2 diabetes
Baseline levels of two plasma sphingolipid species are independent predictors of AF development in patients with T2D. These findings could help identify T2D patients at elevated risk of adverse hepatic and extrahepatic outcomes, potentially allowing for new targeted therapeutic interventions.
Authors
- Bruno Vergès (ORCID: https://orcid.org/0000-0001-8957-629X)
- Jean‐Paul Pais‐de‐Barros
- Jean‐Michel Petit (ORCID: https://orcid.org/0000-0002-1809-2455)
- Alexia Rouland (ORCID: https://orcid.org/0000-0003-0727-2052)
- Damien Denimal (ORCID: https://orcid.org/0000-0001-5454-954X)
- Laurence Duvillard (ORCID: https://orcid.org/0000-0001-9320-793X)
- Hélène Choubley (ORCID: https://orcid.org/0000-0002-3202-1434)
- Isabelle Simoneau (ORCID: https://orcid.org/0000-0002-9092-1908)
- Sarah Béland‐Bonenfant (ORCID: https://orcid.org/0000-0001-6221-6497)
- Benjamin Bouillet (ORCID: https://orcid.org/0000-0002-4317-6714)
Institutions
- Inserm (FR)
- Université de Bourgogne (FR)
- CHU Dijon Bourgogne (FR)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1111/dom.70156
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Société Francophone du Diabète