Retrospective Analysis of the Association of Preoperative Sex Hormone Therapy With the Development of Postoperative Acute Kidney Injury
Preoperative antiandrogen therapy in men and vaginal estrogen therapy in women older than 55 years were associated with reduced odds of postoperative AKI after noncardiac surgery. Our findings provide correlative evidence that sex hormones might modify postoperative AKI outcomes, while revealing complexity in drug and patient selection.
Authors
- Abhishek N. Prasad (ORCID: https://orcid.org/0000-0002-4147-2077)
- Jamie R. Privratsky (ORCID: https://orcid.org/0000-0003-3598-4911)
- Vijay Krishnamoorthy (ORCID: https://orcid.org/0000-0002-1365-4121)
- Pattrapun Wongsripuemtet (ORCID: https://orcid.org/0000-0003-3301-3214)
- Thomas M Price (ORCID: https://orcid.org/0000-0003-1888-306X)
- Shreya Khandelwal (ORCID: https://orcid.org/0000-0002-3882-2080)
- Karthik Raghunathan (ORCID: https://orcid.org/0000-0003-2809-5374)
- Matthew Fuller (ORCID: https://orcid.org/0000-0001-9066-5409)
- André J. Savadjian
- Rebecca Schroeder
- Tetsu Ohnuma
- Ravi Jasti
Institutions
- Duke University (US)
- Duke Medical Center (US)
- Durham VA Medical Center (US)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1213/ane.0000000000007727
- Citations
- 1
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39