Topical Application of a Novel Harderian-Derived Nonpolar Lipid Prolongs Tear Film Breakup Time in Normal Beagle Dogs
Treatment with rNPL593 was well tolerated at all doses tested and resulted in an increased TFBUT that was most pronounced with the 3 mg/mL concentration at 6- and 24-h post-dose.
Authors
- Sara M. Thomasy (ORCID: https://orcid.org/0000-0001-5617-9677)
- Daniel M. Albert (ORCID: https://orcid.org/0000-0001-7891-5161)
- Sangwan Park (ORCID: https://orcid.org/0000-0003-0381-0386)
- Brian C. Leonard (ORCID: https://orcid.org/0000-0003-2080-8480)
- Nayone Lantyer Araujo (ORCID: https://orcid.org/0000-0002-3305-3147)
- Erin A. Hisey (ORCID: https://orcid.org/0000-0003-1090-1745)
- Atul N. Parikh (ORCID: https://orcid.org/0000-0002-5927-4968)
- Christopher J. Murphy
- Thomas R. Gadek
- Charles O’Neill (ORCID: https://orcid.org/0000-0003-2586-6874)
Institutions
- Oregon Health & Science University (US)
- Q Therapeutics (United States) (US)
- University of California, Davis (US)
Publication Details
- Journal
- Journal of Ocular Pharmacology and Therapeutics
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1177/10807683251382004
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00