Youthful systemic milieu in younger recipients alleviates acute kidney injury via attenuating apoptosis and oxidative stress in a rat kidney transplantation model
Younger systemic internal milieu in young recipients alleviated AKI after kidney transplantation by ameliorating oxidative stress and apoptosis via immune response regulation. Cytokines may play a protective role in AKI after kidney transplantation. The use of cytokines in transplantation deserves further experimental evaluation and clinical considerations.
Authors
- Shengde Wu (ORCID: https://orcid.org/0000-0002-0083-561X)
- Jun Pei (ORCID: https://orcid.org/0000-0001-8261-5903)
- Yi Hua (ORCID: https://orcid.org/0009-0006-8029-1136)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-6143-9055)
- Chengjun Yu (ORCID: https://orcid.org/0000-0002-3405-1450)
- Guanghui Wei (ORCID: https://orcid.org/0000-0002-7822-8684)
- Sheng Wen
Institutions
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1371/journal.pone.0331020
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00