Dual versus mono antiplatelet therapy within 72 hours after onset for mild ischaemic stroke or transient ischaemic attack: meta-analysis of randomised controlled trials

For acute mild stroke (NIHSS ≤5) or patients with TIA within 72 hours of ictus, early DAPT initiation demonstrates net clinical benefit through reducing ischaemic events, despite an increase in bleeding complications, without affecting mortality.

Authors

Yingying Yang (ORCID: https://orcid.org/0000-0001-9431-9925)
Yilong Wang (ORCID: https://orcid.org/0000-0002-3267-0039)
Jinghan Zhu
Ying Gao (ORCID: https://orcid.org/0000-0002-5409-7675)
Yuesong Pan

Institutions

Capital Medical University (CN)
Beijing Tian Tan Hospital (CN)
National Clinical Research Center for Digestive Diseases (CN)
Chinese Institute for Brain Research (CN)

Publication Details

Journal: Stroke and Vascular Neurology
Published: 2025-09-23
DOI: https://doi.org/10.1136/svn-2025-004143
Primary Topic: Acute Ischemic Stroke Management
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
National Science and Technology Major Project
National Key Research and Development Program of China

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Dual versus mono antiplatelet therapy within 72 hours after onset for mild ischaemic stroke or transient ischaemic attack: meta-analysis of randomised controlled trials

Yingying Yang, Yilong Wang, Jinghan Zhu, Ying Gao et al.

Sep 23, 2025

Stroke and Vascular Neurology

Acute Ischemic Stroke Management

article

Dual versus mono antiplatelet therapy within 72 hours after onset for mild ischaemic stroke or transient ischaemic attack: meta-analysis of randomised controlled trials

Yingying Yang, Yilong Wang, Jinghan Zhu, Ying Gao, Yuesong Pan

September 23, 2025article en

Abstract

For acute mild stroke (NIHSS ≤5) or patients with TIA within 72 hours of ictus, early DAPT initiation demonstrates net clinical benefit through reducing ischaemic events, despite an increase in bleeding complications, without affecting mortality.

Stroke and Vascular Neurology

Capital Medical University (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Chinese Institute for Brain Research (CN)

National Natural Science Foundation of China, National Science and Technology Major Project, National Key Research and Development Program of China

Openalex Percentile: Top 65%

Acute Ischemic Stroke Management

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Dual versus mono antiplatelet therapy within 72 hours after onset for mild ischaemic stroke or transient ischaemic attack: meta-analysis of randomised controlled trials — Yingying Yang, Yilong Wang, et al. · Stroke and Vascular Neurology (2025) | TGRS Research Map | TGRS