The Complexity of Weak Rhesus Positivity in Pregnancy: Challenges and Management—A Case Report

Most women in the United States are Rh+, which eliminates the need for RhIG during pregnancy. Nevertheless, approximately 550,000 women annually are categorized as Rh-, and 16,700 of these cases may represent weak Rh positivity. Identifying weakly Rh+ individuals holds potential to reallocate scarce RhIG resources to those who require them. In this report we explore the clinical implications of weak Rh positivity, emphasizing maternal-fetal health considerations and the nuanced approach required to manage such cases effectively in the ED.