A comparison of five different drug-drug interaction checkers for selective serotonin reuptake inhibitors
The findings reveal substantial discrepancies in the identification and severity categorization of SSRIs-related DDIs among ICs, underscoring the challenges faced by healthcare providers in ensuring safe prescribing practices. The study advocates for the standardization of IC databases and severity criteria to enhance consistency and reliability.
Authors
- Shanshan Xu (ORCID: https://orcid.org/0000-0001-6137-2738)
- Zhihui Song
- Ente Wang (ORCID: https://orcid.org/0000-0001-8096-3154)
- Jiawei Wang (ORCID: https://orcid.org/0000-0003-2627-4897)
- Dong Wang (ORCID: https://orcid.org/0009-0001-4901-4759)
- Jie Bai (ORCID: https://orcid.org/0009-0003-4320-9082)
- Yiman Li (ORCID: https://orcid.org/0009-0000-7243-6784)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fphar.2025.1690975
- Citations
- 1
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 1.39