Quantitative ¹³C-urea breath test values predict peptic ulcer risk in Helicobacter pylori -infected children: a retrospective study
A DOB cutoff of 5.285‰ provides excellent diagnostic accuracy for pediatric <i>H. pylori</i> infection. Higher DOBs correlate strongly with increased bacterial load, mucosal inflammation, and peptic ulcer (PU) risk up to ∼36.39‰, indicating a saturation effect. Quantitative DOB thus offers diagnostic and prognostic utility, supporting its integration into regional pediatric guidelines.
Authors
- Youtao Chen
- Haibo Li (ORCID: https://orcid.org/0000-0002-6512-3912)
- Xiaoting Pan
- Hong Ye
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-24
- DOI
- https://doi.org/10.3389/fped.2025.1684120
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fujian Medical University