Adipose tissue signaling in aldosterone-producing adenomas: paracrine and endocrine effects
RNA sequencing identified significant gene expression differences in fat compartments of APA patients, implying endocrine and paracrine effects of APAs. These findings might partly explain cardiovascular consequences of primary aldosteronism and could lead to new diagnostic strategies, especially through accessible scAT.
Authors
- Nada Rayes
- Martin Faßnacht (ORCID: https://orcid.org/0000-0001-6170-6398)
- Nicolas Schlegel (ORCID: https://orcid.org/0000-0001-5705-3945)
- Ulrich Dischinger (ORCID: https://orcid.org/0009-0008-4885-9355)
- Simon Kloock (ORCID: https://orcid.org/0009-0005-4610-0888)
- Leonid Kagan (ORCID: https://orcid.org/0000-0003-3863-4757)
- Matthias Blüher (ORCID: https://orcid.org/0000-0003-0208-2065)
- Niklas Geiger (ORCID: https://orcid.org/0009-0004-2163-8422)
- Christian G. Ziegler
- Anke Tönjes
- M. K. Srivastava
Institutions
- Leipzig University of Applied Sciences (DE)
- University of Würzburg (DE)
- Städtisches Klinikum Dresden (DE)
- University Hospital Leipzig (DE)
- Universitätsklinikum Würzburg (DE)
- University Hospital Carl Gustav Carus (DE)
- Hochschule für Technik und Wirtschaft Dresden – University of Applied Sciences (DE)
- Technische Universität Dresden (DE)
- Leipzig University (DE)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-09-24
- DOI
- https://doi.org/10.1093/ejendo/lvaf190
- Citations
- 1
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.29