Stationary prospective cardiac gated computed tomography—dynamic study in phantoms and in vivo

Objective. This study explores the feasibility of a stationary gantry cardiac gated computed tomography (CT) with carbon nanotube (CNT) linear x-ray source arrays. Approach. We developed a stationary gantry CT system utilizing multipixel CNT x-ray sources. Given the advantages of straightforward x-ray pulse control with these sources, we investigated the potential for gated prospective imaging. We implemented prospective respiratory and cardiac gating control and evaluated the system through dynamic phantom imaging studies followed by imaging of a porcine model. Main Results. The findings revealed minimal anatomical motion artifacts in the heart and lungs, confirming successful physiologic gated acquisition in stationary gantry cardiac CT. This indicates the potential of this imaging approach for reducing artifacts and improving image quality. Significance. This study demonstrates the feasibility of prospective physiological gating with CNT x-ray sources in a stationary gantry setup for cardiac imaging. This approach could potentially alleviate the need for beta blocker administration during cardiac CT scans, thereby increasing the flexibility of the imaging system and enabling the imaging of a wider variety of patient cardiac conditions.

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Publication Details

Journal
UNC Libraries
Published
2025-08-09
DOI
https://doi.org/10.17615/fgzj-a414
Primary Topic
Advanced X-ray and CT Imaging
Type
article
Field-Weighted Citation Impact
0.00

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article

Stationary prospective cardiac gated computed tomography—dynamic study in phantoms and in vivo

Christina R. Inscoe, Otto Zhou, Mohamed F. Attia, Alex J. Billingsley et al.
UNC Libraries
Advanced X-ray and CT Imaging
article

Stationary prospective cardiac gated computed tomography—dynamic study in phantoms and in vivo

Christina R. Inscoe, Otto Zhou, Mohamed F. Attia, Alex J. Billingsley, Yueh Z. Lee, Jianping Lu
article en

Abstract

Objective. This study explores the feasibility of a stationary gantry cardiac gated computed tomography (CT) with carbon nanotube (CNT) linear x-ray source arrays. Approach. We developed a stationary gantry CT system utilizing multipixel CNT x-ray sources. Given the advantages of straightforward x-ray pulse control with these sources, we investigated the potential for gated prospective imaging. We implemented prospective respiratory and cardiac gating control and evaluated the system through dynamic phantom imaging studies followed by imaging of a porcine model. Main Results. The findings revealed minimal anatomical motion artifacts in the heart and lungs, confirming successful physiologic gated acquisition in stationary gantry cardiac CT. This indicates the potential of this imaging approach for reducing artifacts and improving image quality. Significance. This study demonstrates the feasibility of prospective physiological gating with CNT x-ray sources in a stationary gantry setup for cardiac imaging. This approach could potentially alleviate the need for beta blocker administration during cardiac CT scans, thereby increasing the flexibility of the imaging system and enabling the imaging of a wider variety of patient cardiac conditions.

UNC Libraries
University of North Carolina at Chapel Hill (US)
U.S. Department of Defense, National Institutes of Health, National Cancer Institute, Congressionally Directed Medical Research Programs
Openalex Percentile: Top 75%
Advanced X-ray and CT Imaging
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Stationary prospective cardiac gated computed tomography—dynamic study in phantoms and in vivo — Christina R. Inscoe, Otto Zhou, et al. · UNC Libraries (2025) | TGRS Research Map | TGRS