[99mTc]Tc-sestamibi SPECT/CT for the diagnosis of kidney tumours: a multi-centre feasibility study (MULTI-MIBI Study)
MULTI-MIBI has demonstrated feasibility of recruitment to a diagnostic evaluation study for T1 renal masses. Preliminary estimates of diagnostic accuracy suggest that MIBI SPECT/CT could reduce the number of patients with benign tumours undergoing surgery without missing a significant number of patients with malignant disease, however these results are limited by the small sample size in this feasibility study and a larger definitive study is needed prior to adoption in practice.
Authors
- Hannah Warren (ORCID: https://orcid.org/0000-0002-4106-2705)
- Ben J Challacombe (ORCID: https://orcid.org/0000-0001-8631-0314)
- Ammar Alanbuki
- James P. Blackmur (ORCID: https://orcid.org/0000-0001-7267-837X)
- Cecilia Vindrola‐Padros (ORCID: https://orcid.org/0000-0001-7859-1646)
- Sabina Dizdarevic (ORCID: https://orcid.org/0000-0002-6715-3744)
- Prasad Patki (ORCID: https://orcid.org/0000-0001-5862-5431)
- Andrew Scarsbrook (ORCID: https://orcid.org/0000-0002-4243-032X)
- Ravi Barod
- Elena Pizzo (ORCID: https://orcid.org/0000-0003-0790-7505)
- Maryam Jessop
- Sigrún Eyrúnardóttir Clark (ORCID: https://orcid.org/0000-0001-5679-2535)
- William H. Wildgoose
- Iosif Mendichovszky (ORCID: https://orcid.org/0000-0002-3777-2827)
- Veeru Kasivisvanathan (ORCID: https://orcid.org/0000-0002-0832-382X)
- Tze Min Wah (ORCID: https://orcid.org/0000-0001-5670-5454)
- Cecil R. Stewart
- Fahim Ul-Hassan
- Soha El Sheikh (ORCID: https://orcid.org/0000-0003-4661-1563)
- Nitasha Singh
- Axel Bex (ORCID: https://orcid.org/0000-0002-8499-2662)
- Linda Park (ORCID: https://orcid.org/0000-0001-8008-343X)
- Faiz Mumtaz (ORCID: https://orcid.org/0000-0002-0211-3936)
- Nick Campain
- Maxine G B Tran (ORCID: https://orcid.org/0000-0002-6034-4433)
- Grant Duncan Stewart (ORCID: https://orcid.org/0000-0003-3188-9140)
- Hakim‐Moulay Dehbi (ORCID: https://orcid.org/0000-0002-0816-0178)
- Helen Ng (ORCID: https://orcid.org/0000-0002-7465-2090)
- Mark Emberton (ORCID: https://orcid.org/0000-0003-4230-0338)
- Thomas Wagner (ORCID: https://orcid.org/0000-0002-3867-6829)
- Tim S. O’Brien
- Patrick Rogers
- Alex Wood
- Kelly Leonard
- Dhruba Dasgupta
Institutions
- Brighton and Sussex Medical School (GB)
- University College Hospital (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- University of Cambridge (GB)
- Leeds Teaching Hospitals NHS Trust (GB)
- Royal Devon & Exeter NHS Foundation Trust (GB)
- The Royal Free Hospital (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- MRC Clinical Trials Unit at UCL (GB)
- The London College (GB)
- University Hospitals Sussex NHS Foundation Trust (GB)
- University College London (GB)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1007/s00259-025-07525-3
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- National Institute for Health and Care Research
- Department of Health and Social Care
- Urology Foundation
- Engineering and Physical Sciences Research Council
- Research for Patient Benefit Programme