Neuroanatomical normative modelling in frontotemporal lobar degeneration: higher heterogeneity in the behavioural variant
The pronounced heterogeneity within and between FTLD subtypes (particularly in bvFTD) increases with disease progression and may reflect distinct underlying pathologies. This supports the development of subtype-specific biomarkers and emphasize the need for personalized diagnostic and therapeutic strategies.
Authors
- James H. Cole (ORCID: https://orcid.org/0000-0003-1908-5588)
- Martina Bocchetta (ORCID: https://orcid.org/0000-0003-1814-5024)
- Srijan Konwar
- Annalena Venneri (ORCID: https://orcid.org/0000-0002-9488-2301)
- Nikolett Hunyadvari
Institutions
- University of Parma (IT)
- UK Dementia Research Institute (GB)
- The London College (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- University College London (GB)
- Brunel University of London (GB)
- University of Sheffield (GB)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1007/s00415-025-13378-5
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alzheimer's Society