Synchronous multiple meningiomas and renal cell carcinoma metastasis to the brain in a 68Ga-DOTATATE scan: illustrative case
68Ga-DOTATATE is highly sensitive for detecting benign and malignant CNS tumors, including small lesions. It aids in planning treatment, defining radiosurgical targets, and monitoring response. In RCC, it yields a higher SUV than 18F-fluorodeoxyglucose positron emission tomography, making it a more effective diagnostic tool. In meningiomas, the SUV correlates with tumor growth rate. However, specificity is limited, and interpretation requires correlation with MRI, CT, and clinical findings. As its use in CNS tumors grows, understanding its capabilities and limitations is crucial for proper application. https://thejns.org/doi/10.3171/CASE25527.
Authors
- Dheerendra Prasad (ORCID: https://orcid.org/0000-0002-6615-4235)
- Neil D. Almeida
- Lindsay Lipinski (ORCID: https://orcid.org/0000-0002-1253-8516)
- Victor Goulenko (ORCID: https://orcid.org/0000-0001-9746-7931)
- Rohil Shekher
- Venkatesh S. Madhugiri (ORCID: https://orcid.org/0000-0002-1517-9707)
- Robert J. Plunkett
Institutions
- Roswell Park Comprehensive Cancer Center (US)
- Jacobs Institute (US)
Publication Details
- Journal
- Journal of Neurosurgery Case Lessons
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3171/case25527
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00