Synchronous multiple meningiomas and renal cell carcinoma metastasis to the brain in a 68Ga-DOTATATE scan: illustrative case

68Ga-DOTATATE is highly sensitive for detecting benign and malignant CNS tumors, including small lesions. It aids in planning treatment, defining radiosurgical targets, and monitoring response. In RCC, it yields a higher SUV than 18F-fluorodeoxyglucose positron emission tomography, making it a more effective diagnostic tool. In meningiomas, the SUV correlates with tumor growth rate. However, specificity is limited, and interpretation requires correlation with MRI, CT, and clinical findings. As its use in CNS tumors grows, understanding its capabilities and limitations is crucial for proper application. https://thejns.org/doi/10.3171/CASE25527.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-09-22
DOI
https://doi.org/10.3171/case25527
Primary Topic
Brain Metastases and Treatment
Type
article
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article

Synchronous multiple meningiomas and renal cell carcinoma metastasis to the brain in a 68Ga-DOTATATE scan: illustrative case

Dheerendra Prasad, Neil D. Almeida, Lindsay Lipinski, Victor Goulenko et al.
Journal of Neurosurgery Case Lessons
Brain Metastases and Treatment
article

Synchronous multiple meningiomas and renal cell carcinoma metastasis to the brain in a 68Ga-DOTATATE scan: illustrative case

Dheerendra Prasad, Neil D. Almeida, Lindsay Lipinski, Victor Goulenko, Rohil Shekher, Venkatesh S. Madhugiri, Robert J. Plunkett
article en

Abstract

68Ga-DOTATATE is highly sensitive for detecting benign and malignant CNS tumors, including small lesions. It aids in planning treatment, defining radiosurgical targets, and monitoring response. In RCC, it yields a higher SUV than 18F-fluorodeoxyglucose positron emission tomography, making it a more effective diagnostic tool. In meningiomas, the SUV correlates with tumor growth rate. However, specificity is limited, and interpretation requires correlation with MRI, CT, and clinical findings. As its use in CNS tumors grows, understanding its capabilities and limitations is crucial for proper application. https://thejns.org/doi/10.3171/CASE25527.

Journal of Neurosurgery Case LessonsVol. 10(12)
Roswell Park Comprehensive Cancer Center (US), Jacobs Institute (US)
Openalex Percentile: Top 63%
Brain Metastases and Treatment
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Synchronous multiple meningiomas and renal cell carcinoma metastasis to the brain in a 68Ga-DOTATATE scan: illustrative case — Dheerendra Prasad, Neil D. Almeida, et al. · Journal of Neurosurgery Case Lessons (2025) | TGRS Research Map | TGRS