Living Alone, Early Tau Pathology, and Loneliness in Cognitively Unimpaired Older Adults During the COVID-19 Pandemic
Greater tau pathology amplified the association between living alone and increased loneliness among CU older adults during the COVID-19 pandemic. AD pathological brain changes may play an unrecognized role in late-life loneliness.
Authors
- Heidi I.L. Jacobs (ORCID: https://orcid.org/0000-0001-7620-3822)
- Jennifer R. Gatchel (ORCID: https://orcid.org/0000-0002-3892-9742)
- Yakeel T. Quiroz (ORCID: https://orcid.org/0000-0001-9714-8244)
- Gad A. Marshall (ORCID: https://orcid.org/0000-0002-9096-2355)
- Patrizia Vannini (ORCID: https://orcid.org/0000-0002-9425-1059)
- Nancy J. Donovan (ORCID: https://orcid.org/0000-0002-6328-1589)
- Benjamin S. Zide (ORCID: https://orcid.org/0009-0003-5621-8850)
- Dorene M. Rentz
- Geoffroy Gagliardi (ORCID: https://orcid.org/0000-0002-2608-8456)
- Keith A. Johnson (ORCID: https://orcid.org/0000-0002-5916-6043)
- Reisa A Sperling
Institutions
- Brigham and Women's Hospital (US)
- Brown University (US)
- Maastricht University Medical Centre (NL)
- McLean Hospital (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- American Journal of Geriatric Psychiatry
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.jagp.2025.09.014
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00