European pilot interlaboratory comparison study on Mpox virus whole genome sequencing

Although results for MPXV clade IIb 2022 outbreak strains are reassuring, the inclusion of MPXV clade I and IIa strains highlights pitfalls for targeted sequencing approaches and subsequent bioinformatic analyses. Our findings underscore the need for standardized external quality assessment studies.

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Publication Details

Journal
Clinical Microbiology and Infection
Published
2025-09-23
DOI
https://doi.org/10.1016/j.cmi.2025.09.011
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
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article

European pilot interlaboratory comparison study on Mpox virus whole genome sequencing

Tessa de Block, Andreas Nitsche, Trestan Pillonel, Rita Cordeiro et al.
Clinical Microbiology and Infection
Poxvirus research and outbreaks
article

European pilot interlaboratory comparison study on Mpox virus whole genome sequencing

Tessa de Block, Andreas Nitsche, Trestan Pillonel, Rita Cordeiro, Koen Vercauteren, Christophe Pasquier, Jonas Fuchs, Belén Rodríguez‐Sánchez, Claire Bertelli, Marcus Panning, Juan Ledesma, Annika Brinkmann, Antônio Mauro Rezende, Janine Michel, Gilbert Greub, Daniel Sobral, Jacques Izopet, Anastasija Maks, Kuiama Lewandowski, Maria Paz Sanches-Seco
article en

Abstract

Although results for MPXV clade IIb 2022 outbreak strains are reassuring, the inclusion of MPXV clade I and IIa strains highlights pitfalls for targeted sequencing approaches and subsequent bioinformatic analyses. Our findings underscore the need for standardized external quality assessment studies.

Clinical Microbiology and InfectionVol. 32(1)
University of Freiburg (DE), National Institute of Health Dr. Ricardo Jorge (PT), UK Health Security Agency (GB), Instituut voor Tropische Geneeskunde (BE), University of Lausanne (CH)
Openalex Percentile: Top 72%
Poxvirus research and outbreaks
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European pilot interlaboratory comparison study on Mpox virus whole genome sequencing — Tessa de Block, Andreas Nitsche, et al. · Clinical Microbiology and Infection (2025) | TGRS Research Map | TGRS