No evidence of molecular markers of piperaquine resistance in southeastern Nigeria
The complete absence of validated PPQresistance markers indicates that piperaquine remains a viable partner drug in DHA‑PPQ for South‑East Nigeria. Nonetheless, because DHA‑PPQ is increasingly available over the counter, ongoing molecular and therapeutic‑efficacy surveillance is imperative to detect any future emergence of resistance.
Authors
- Jana Held (ORCID: https://orcid.org/0000-0002-7970-1429)
- Linda Onyeka Anagu (ORCID: https://orcid.org/0000-0002-2243-1616)
- Juliana Inoue (ORCID: https://orcid.org/0000-0001-6786-5509)
- Laís Pessanha de Carvalho (ORCID: https://orcid.org/0000-0002-3857-5462)
- Miriam Rodi
- Moses Ikegbunam
- Vasileios Tzirtziganis
Institutions
- Nnamdi Azikiwe University (NG)
- Centre de Recherche Médicales de Lambaréné (GA)
- German Center for Infection Research (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1186/s12936-025-05579-0
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00