Trajectory of the systemic immune-inflammation index and in-hospital mortality in patients with sepsis

In patients with sepsis, the risk of in-hospital mortality differs according to the SII within 24 hours of admission and the SII trajectory. The risk of in-hospital mortality was greatest in patients whose SII increased continuously and those whose SII stabilized at a high level, and was lowest in patients with an SII stabilized at a medium-high level. The SII within 24 hours after admission had a U-shaped relationship with in-hospital mortality.