Association of lactate to albumin ratio with short-term and long-term mortality in critically ill patients with heart failure complicated by sepsis: a retrospective study using the MIMIC-IV database

In critically ill patients with HF complicated by sepsis, LAR is a reliable and independent predictor of mortality. Patients in the highest LAR quartile (>0.97) have a significantly increased risk of death, providing a clinically useful reference for rapid identification of high-risk individuals. The significant interaction observed in hypertensive subgroups highlights the need for heightened clinical attention. Overall, LAR may serve as a practical biomarker for risk stratification and prognostic evaluation in this vulnerable population.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-09-23
DOI
https://doi.org/10.3389/fcvm.2025.1636375
Citations
1
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35
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article

Association of lactate to albumin ratio with short-term and long-term mortality in critically ill patients with heart failure complicated by sepsis: a retrospective study using the MIMIC-IV database

Yuming Wu, Qiuyan Wen
1 citations
Frontiers in Cardiovascular Medicine
Sepsis Diagnosis and Treatment
1.35
article

Association of lactate to albumin ratio with short-term and long-term mortality in critically ill patients with heart failure complicated by sepsis: a retrospective study using the MIMIC-IV database

Yuming Wu, Qiuyan Wen
article en
1 citations

Abstract

In critically ill patients with HF complicated by sepsis, LAR is a reliable and independent predictor of mortality. Patients in the highest LAR quartile (>0.97) have a significantly increased risk of death, providing a clinically useful reference for rapid identification of high-risk individuals. The significant interaction observed in hypertensive subgroups highlights the need for heightened clinical attention. Overall, LAR may serve as a practical biomarker for risk stratification and prognostic evaluation in this vulnerable population.

Frontiers in Cardiovascular MedicineVol. 12
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN)
Openalex Percentile: Top 15%
Sepsis Diagnosis and Treatment
1.35
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