Dual fungal endocarditis in a pediatric dialysis patient: First case of Aspergillus flavus and Candida parapsilosis co-infection
We report the first pediatric case of dual fungal infective endocarditis (IE) caused by <i>Aspergillus flavus</i> and <i>Candida parapsilosis</i> in a dialysis-dependent child from a conflict-affected region. Diagnosis was supported by galactomannan monitoring, histopathology, and molecular sequencing. Management required early surgery and prolonged dual antifungal therapy. Despite the rarity and severity of such coinfections, the patient survived. This case highlights the importance of early recognition, multidisciplinary care, and aggressive treatment in pediatric fungal IE.
Authors
- Fatima A. Al Dhaheri (ORCID: https://orcid.org/0000-0002-5412-6157)
- Akela Ghazawi (ORCID: https://orcid.org/0000-0003-2552-4807)
- Hari Pankaj Vanam (ORCID: https://orcid.org/0000-0002-4897-335X)
- Tasneem Basha
- Abdullah Ahmed Al‐Ghamdi
- Amina Bakro
Institutions
- Al Ain University (AE)
- United Arab Emirates University (AE)
- Shaikh Khalifa Medical City (AE)
- Al Ain Hospital (AE)
- Abu Dhabi Health Services (AE)
Publication Details
- Journal
- Medical Mycology Case Reports
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.mmcr.2025.100735
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00