Exploring the antibacterial potential of arthrocolins against extensively drug-resistant Pseudomonas aeruginosa: mechanistic insights into amino acid metabolism disruption
These findings suggest that Acs exerts potent antibacterial effects through disruption of metabolic homeostasis and structural integrity. The study highlights the potential of Acs as a promising candidate for the treatment of XDR-PA infections, offering a new avenue for therapeutic development. The bacterial names cannot be italicized in the annotations. The revised abstract has been uploaded separately as an attachment.
Authors
- Jianmei Liu (ORCID: https://orcid.org/0000-0002-8179-031X)
- Xue‐Mei Niu
- W. H. Tian
- Yunwen Zhang
- Bao-Rui Yang
- Wenli Yuan (ORCID: https://orcid.org/0000-0002-6396-1218)
- De‐Yao Deng
- Qunfu Wu (ORCID: https://orcid.org/0009-0006-3088-0119)
- Gengyi Wu (ORCID: https://orcid.org/0009-0001-9681-592X)
Institutions
- Yunnan University (CN)
- Second People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fmicb.2025.1618419
- Citations
- 2
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 2.37
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Yunnan University
- Institute of Zoology, Chinese Academy of Sciences
- Kunming Institute of Zoology, Chinese Academy of Sciences