Boruta algorithm–guided antibiotic selection in antibiotic-loaded bone cement for diabetic foot ulcers: microbiota and susceptibility analysis

In the treatment of DFI, Gram-positive bacteria infection is more common in clinical practice, especially anti-infective treatment against <i>Staphylococcus aureus</i> needs to be paid attention to. Based on our findings, it is advised that the DFU population who requires bone cement antibiotic treatment be treated according to age, with GEN and TOB being recommended for Gram-negative bacteria and MFX, AMP, and QDA for Gram-positive bacteria.