Fatal immune checkpoint inhibitor-related pneumonitis following postoperative nivolumab administration in a patient with unclassifiable interstitial pneumonia and resected lung squamous cell carcinoma: A case report

This case highlights the potentially fatal risk of postoperative nivolumab therapy in patients with pre-existing ILD, even in the setting of unclassifiable interstitial pneumonia. Careful risk-benefit assessment is warranted when considering adjuvant immune checkpoint inhibitors in this population.

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Publication Details

Journal
Respiratory Medicine Case Reports
Published
2025-01-01
DOI
https://doi.org/10.1016/j.rmcr.2025.102294
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Fatal immune checkpoint inhibitor-related pneumonitis following postoperative nivolumab administration in a patient with unclassifiable interstitial pneumonia and resected lung squamous cell carcinoma: A case report

Kenzo Hiroshima, Yasuo Sekine, Eitetsu Koh
Respiratory Medicine Case Reports
Cancer Immunotherapy and Biomarkers
article

Fatal immune checkpoint inhibitor-related pneumonitis following postoperative nivolumab administration in a patient with unclassifiable interstitial pneumonia and resected lung squamous cell carcinoma: A case report

Kenzo Hiroshima, Yasuo Sekine, Eitetsu Koh
article en

Abstract

This case highlights the potentially fatal risk of postoperative nivolumab therapy in patients with pre-existing ILD, even in the setting of unclassifiable interstitial pneumonia. Careful risk-benefit assessment is warranted when considering adjuvant immune checkpoint inhibitors in this population.

Respiratory Medicine Case ReportsVol. 58
Tokyo Women's Medical University (JP), Tokyo Women's Medical University Yachiyo Medical Center
Openalex Percentile: Top 65%
Cancer Immunotherapy and Biomarkers
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