Oscillatory components of bidirectional cardio-respiratory coupling in depression and suicidal ideation: insights from swarm decomposition and entropy analysis
This study reveals that frequency-specific disruptions in bidirectional cardiorespiratory coupling, along with reduced signal complexity and entropy, are characteristic of MDDSI. These features may reflect impaired autonomic adaptability and emotional regulation. Phase-based coupling metrics and SwD show promise as physiological biomarkers for early identification of high-risk depressive states in digital psychiatry.
Authors
- Herbert F. Jelinek (ORCID: https://orcid.org/0000-0001-5457-6193)
- Mohanad Alkhodari (ORCID: https://orcid.org/0000-0002-5248-6327)
- Ahsan H. Khandoker (ORCID: https://orcid.org/0000-0002-0636-1646)
- Leontios J. Hadjileontiadis (ORCID: https://orcid.org/0000-0002-9932-9302)
Institutions
- Khalifa University of Science and Technology (AE)
- Aristotle University of Thessaloniki (GR)
- University of Oxford (GB)
Publication Details
- Journal
- Frontiers in Network Physiology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fnetp.2025.1620862
- Citations
- 1
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Khalifa University of Science, Technology and Research