Mendelian randomization combined with single-cell sequencing analysis revealed prognostic genes related to myeloid cell differentiation in prostate cancer and experimental verification

This study identified 5 prognostic genes and a risk model, suggesting a fresh thought on the subsequent development of PCa related drugs.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2025-09-23
DOI
https://doi.org/10.3389/fimmu.2025.1619194
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Mendelian randomization combined with single-cell sequencing analysis revealed prognostic genes related to myeloid cell differentiation in prostate cancer and experimental verification

Gongquan Xu, Jianbai Chen, Xiaoping Gao, Jianxin Qiu et al.
Frontiers in Immunology
Ferroptosis and cancer prognosis
article

Mendelian randomization combined with single-cell sequencing analysis revealed prognostic genes related to myeloid cell differentiation in prostate cancer and experimental verification

Gongquan Xu, Jianbai Chen, Xiaoping Gao, Jianxin Qiu, Wei Zhang, Zhiming Zhang, Zhiyong Nie, Leiming Kang
article en

Abstract

This study identified 5 prognostic genes and a risk model, suggesting a fresh thought on the subsequent development of PCa related drugs.

Frontiers in ImmunologyVol. 16
Tang Du Hospital (CN), Air Force Medical University (CN)
Openalex Percentile: Top 63%
Ferroptosis and cancer prognosis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.