Predictive factors and outcomes of immune-related adverse events in Chinese patients treated with immune checkpoint inhibitors: a real-world retrospective study

Younger age and brain metastases were associated with a higher incidence of irAEs. Organ-specific irAEs were characterized by distinct sets of clinical and laboratory predictors. Inflammatory markers correlated with poorer PFS. The type of irAEs was not associated with PFS. Chinese ICIs were not independently associated with an increased risk of specific organ toxicities.