Histological response of the periodontal tissue to mandibular incisor movement using clear aligners of varying thickness in a rabbit model

Both aligners achieved effective tooth movement. The 0.38-mm aligners exerted smaller forces and enabled slightly faster movements than the 0.68-mm aligners. Although both groups showed minimal root resorption, the 0.68-mm group exhibited larger resorption craters. Furthermore, the 0.38-mm group exhibited less histological deformation and inflammation in the periodontal tissues. These results suggest that aligner thickness can be tailored to customize treatments. Further studies with longer observation periods and more refined methodologies are warranted.