Safety, Tolerability, and Efficacy of Shorter Infusion Durations of Pegloticase Administered to Patients With Uncontrolled Gout Receiving Methotrexate: AGILE Trial

Safety, tolerability, and efficacy results of pegloticase infused for 60 minutes were comparable to traditional infusion durations (120 min), making shorter infusion times feasible.

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Publication Details

Journal
JCR Journal of Clinical Rheumatology
Published
2025-09-23
DOI
https://doi.org/10.1097/rhu.0000000000002283
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety, Tolerability, and Efficacy of Shorter Infusion Durations of Pegloticase Administered to Patients With Uncontrolled Gout Receiving Methotrexate: AGILE Trial

Supra Verma, O. Troum, Afroz S. Mohammad, Brian D. LaMoreaux et al.
JCR Journal of Clinical Rheumatology
Gout, Hyperuricemia, Uric Acid
article

Safety, Tolerability, and Efficacy of Shorter Infusion Durations of Pegloticase Administered to Patients With Uncontrolled Gout Receiving Methotrexate: AGILE Trial

Supra Verma, O. Troum, Afroz S. Mohammad, Brian D. LaMoreaux, John K. Botson, Fang Fang
article en

Abstract

Safety, tolerability, and efficacy results of pegloticase infused for 60 minutes were comparable to traditional infusion durations (120 min), making shorter infusion times feasible.

JCR Journal of Clinical RheumatologyVol. 32(1)
University of Southern California (US), Amgen (United States) (US), Providence College (US), Saint John's Health Center (US), Alaska Breast Care & Surgery (US)
Openalex Percentile: Top 72%
Gout, Hyperuricemia, Uric Acid
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Safety, Tolerability, and Efficacy of Shorter Infusion Durations of Pegloticase Administered to Patients With Uncontrolled Gout Receiving Methotrexate: AGILE Trial — Supra Verma, O. Troum, et al. · JCR Journal of Clinical Rheumatology (2025) | TGRS Research Map | TGRS