Successful Maternal and Neonatal Outcomes in a Myasthenia Gravis Patient Presenting in Early Pregnancy: A Case Report

Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder that poses significant challenges during pregnancy due to its variable disease course and potential neonatal complications. Authors hereby, report a case of a 25-year-old primigravida with known MG on immunosuppressive therapy who presented at 8 weeks gestation. Her antenatal period was complicated by worsening respiratory symptoms during the third trimester. She underwent an emergency caesarean section at term due to foetal distress. The neonate, though initially stable, developed respiratory distress and was found to have maternal antibodies, requiring treatment with pyridostigmine. The present case highlights the importance of multidisciplinary care and preparedness for neonatal myasthenia in pregnancies complicated by maternal MG.

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Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2025-09-23
DOI
https://doi.org/10.7860/jcdr/2025/81720.21874
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
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article

Successful Maternal and Neonatal Outcomes in a Myasthenia Gravis Patient Presenting in Early Pregnancy: A Case Report

Vidya Gaikwad, Pradeep Kumar Tiwari, Ashton Dsouza
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Myasthenia Gravis and Thymoma
article

Successful Maternal and Neonatal Outcomes in a Myasthenia Gravis Patient Presenting in Early Pregnancy: A Case Report

Vidya Gaikwad, Pradeep Kumar Tiwari, Ashton Dsouza
article en

Abstract

Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder that poses significant challenges during pregnancy due to its variable disease course and potential neonatal complications. Authors hereby, report a case of a 25-year-old primigravida with known MG on immunosuppressive therapy who presented at 8 weeks gestation. Her antenatal period was complicated by worsening respiratory symptoms during the third trimester. She underwent an emergency caesarean section at term due to foetal distress. The neonate, though initially stable, developed respiratory distress and was found to have maternal antibodies, requiring treatment with pyridostigmine. The present case highlights the importance of multidisciplinary care and preparedness for neonatal myasthenia in pregnancies complicated by maternal MG.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Openalex Percentile: Top 63%
Myasthenia Gravis and Thymoma
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Successful Maternal and Neonatal Outcomes in a Myasthenia Gravis Patient Presenting in Early Pregnancy: A Case Report — Vidya Gaikwad, Pradeep Kumar Tiwari, et al. · JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2025) | TGRS Research Map | TGRS