Impact of molecular and immune signature on endometrial biopsies with atypical hyperplasia with and without concurrent endometroid carcinoma
Pre-operative AEH/EIN biopsy specimens exhibit different molecular and immune profiles depending on the coexistence of concurrent EC. Further characterization of these signatures may lead to advances in diagnostic precision and prognostic capability.
Authors
- Larissa Mattei (ORCID: https://orcid.org/0000-0002-0867-0311)
- Logan Corey (ORCID: https://orcid.org/0000-0003-2880-7546)
- Subhayu Bandyopadhyay (ORCID: https://orcid.org/0000-0003-1626-6543)
- Premal H. Thaker (ORCID: https://orcid.org/0000-0002-0568-6959)
- Nicholas K. Adzibolosu (ORCID: https://orcid.org/0000-0002-3829-5786)
- Joellen Fresia
- Ira Winer (ORCID: https://orcid.org/0000-0001-6056-8296)
- Rami Musallam
- Matthew James Oberley (ORCID: https://orcid.org/0000-0001-6419-2513)
- Sharon Wu (ORCID: https://orcid.org/0000-0002-8336-6301)
- Terrence Wong (ORCID: https://orcid.org/0000-0002-4509-208X)
- Kurt Hodges
- Rouba-Ali Fehmi (ORCID: https://orcid.org/0009-0003-0642-535X)
- Mira Kheil (ORCID: https://orcid.org/0000-0001-7426-5923)
- Robert Morris
- Joanne Xiu
Institutions
- Wayne State University (US)
- Washington University in St. Louis (US)
- University of Michigan (US)
- University of Massachusetts Boston (US)
- The Barbara Ann Karmanos Cancer Institute (US)
- Caris Life Sciences (United States) (US)
Publication Details
- Journal
- Gynecologic Oncology Reports
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.gore.2025.101959
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00