Efficacy Confirmatory Study of Foods Containing <i>Garcinia </i><i>indica</i> Extract on Liver Function: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Objectives: A randomized, double-blind, placebo-controlled, parallel-group study was conducted to evaluate the impact of foods containing Garcinia indica extract on liver function in healthy participants. Methods: Eighty healthy participants (alanine aminotransferase (ALT) ≤ 50 U/L, aspartate aminotransferase (AST) ≤ 50 U/L, gamma-glutamyl transferase (γ-GTP) ≤ 100 U/L, and body mass index G. indica extract (18.0 mg/day of garcinol) for 12 weeks, and the placebo group, who consumed food without G. indica extract for the same duration. The primary outcome—the serum ALT and AST levels—was evaluated along with secondary outcomes, including γ-GTP and a Likert scale questionnaire on stool form. Results: There was a statistically significant difference in the ALT and AST levels (P Conclusions: Overall, these findings indicate that foods containing G. indica extract contributed to a slight reduction in ALT and AST levels, which, although within the normal range, were marginally elevated in healthy participants.