ANTI-AGING DRUGS: A COMPREHENSIVE PHARMACOLOGICAL ANALYSIS
Objective: The primary aim of this study is to provide a comprehensive analysis of the pharmacological interventions targeting the mechanisms of aging. 1) To categorize and describe the different classes of anti-aging drugs, including antioxidants, senolytics, telomerase activators, and hormone replacement therapies. 2) To analyze recent research findings on anti-aging therapeutics. 3) To analyze growth trajectory of anti-aging drugs globally. Methods: This analysis was conducted by systematically searching scientific databases, including PubMed, Scopus, and Web of Science, for articles published between 2000 and 2025 related to anti-aging drugs and their mechanisms of action. Results: The research analysis identified ten major classes of anti-aging drugs, with senolytics and caloric restriction mimetics showing the most promise. Emerging therapies like NAD⁺ precursors, stem cell treatments, and antibody-based approaches are under active investigation. The global anti-aging drug market is growing rapidly, driven by innovation and increased demand for longevity solutions. Conclusion: The exploration of anti-aging drugs through a pharmacological lens highlights the significant advancements and challenges in this field.
Authors
- Chennuri Rajesh
- Rakesh Sharma (ORCID: https://orcid.org/0000-0002-5306-3457)
- S Tiwari (ORCID: https://orcid.org/0000-0002-1455-2602)
- Tushar Chandrakant Baheti
Institutions
- Chirayu Medical College & Hospital (IN)
- Sri Siddhartha Medical College (IN)
Publication Details
- Journal
- International Journal of Current Pharmaceutical Research
- Published
- 2025-09-15
- DOI
- https://doi.org/10.22159/ijcpr.2025v17i5.7047
- Citations
- 1
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.95