NAD+-Dependent Lysine Acetylation Regulates Glucose Uptake and Fatty Acid Oxidation in Cardiomyocytes
In cardiomyocytes, protein hyperacetylation, resulting from either FA exposure or sirtuin inhibition, impairs metabolic-stress-stimulated glucose uptake and is associated with increased FA oxidation.
Authors
- Christophe Montessuit (ORCID: https://orcid.org/0000-0002-2580-7711)
- E. Vanni (ORCID: https://orcid.org/0000-0002-5194-6651)
Institutions
- University of Geneva (CH)
- UCLouvain (BE)
Publication Details
- Journal
- Metabolites
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3390/metabo15100636
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Université de Genève
- Fondation Ernst et Lucie Schmidheiny
- Canton de Genève