Simultaneous Quantification of Bictegravir and Emtricitabine Using a Simple and Economical Liquid Chromatography–Ultraviolet Method for Therapeutic Drug Monitoring in Patients with Human Immunodeficiency Virus
A simple and economical liquid chromatography-ultraviolet method was successfully developed for simultaneous quantification of BIC and FTC in human plasma. This method can be extensively used in therapeutic drug monitoring, as in the case of MS-based instrumental deficiency or damage, and in pharmacokinetic studies.
Authors
- Tong Zhang (ORCID: https://orcid.org/0000-0002-9657-5129)
- Wei Liu (ORCID: https://orcid.org/0000-0002-8925-5450)
- Haihong Bai (ORCID: https://orcid.org/0000-0003-0749-6718)
- Yang Zhang (ORCID: https://orcid.org/0000-0003-4521-9228)
- Zihe Wang (ORCID: https://orcid.org/0009-0007-6518-7119)
- Yuan Fang (ORCID: https://orcid.org/0000-0002-8070-2680)
Institutions
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1097/ftd.0000000000001388
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00