Predicting the Effects of Customized Corneal Cross-Linking on Corneal Geometry
Customized CXL induces a flattening of about 2 diopters in the cone region six months after surgery. The model adequately captured the curvature corrections induced by the treatment in the keratoconus cone region, but showed reduced accuracy in predicting global corneal metrics, particularly for customized CXL. The induced flattening effects depend on the IOP, keratoconus-induced biomechanical weakening, and the fluence delivered to the cone.
Authors
- Farhad Hafezi (ORCID: https://orcid.org/0000-0001-8935-4558)
- Matteo Frigelli (ORCID: https://orcid.org/0000-0002-6725-3112)
- M. Enes Aydemir (ORCID: https://orcid.org/0000-0001-5117-9256)
- Emílio A. Torres-Netto (ORCID: https://orcid.org/0000-0002-9007-5895)
- Sabine Kling (ORCID: https://orcid.org/0000-0001-7202-7200)
- Philippe Büchler (ORCID: https://orcid.org/0000-0002-8390-4827)
- J. Rozema (ORCID: https://orcid.org/0000-0001-8124-8646)
- María Ángeles Montañés Gracia
Institutions
- University of Geneva (CH)
- University of Bern (CH)
- University of Antwerp (BE)
- Antwerp University Hospital (BE)
- New York University (US)
- Lonza (Switzerland) (CH)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1167/iovs.66.12.51
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission