Analytical expression of the β coefficient of cell survival curves predicted by the NanOx model in the low‐energy range
We derived in this work an analytical expression for the fast calculation of the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mi>β</mml:mi> <mml:annotation>$\beta$</mml:annotation></mml:semantics> </mml:math> coefficient for ion irradiations. Although the analytical expression resulted from the NanOx model, it can be also applied to any model used to compute <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mi>α</mml:mi> <mml:annotation>$\alpha$</mml:annotation></mml:semantics> </mml:math> . Overall, the approach presented in this work may provide a reasonable description of the behavior of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mi>β</mml:mi> <mml:annotation>$\beta$</mml:annotation></mml:semantics> </mml:math> with LET despite the large spread observed in experimental data.
Authors
- Michaël Beuve (ORCID: https://orcid.org/0000-0002-0516-6232)
- Étienne Testa (ORCID: https://orcid.org/0000-0003-0815-7056)
- Mario Alcocer‐Ávila (ORCID: https://orcid.org/0000-0003-3999-552X)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1002/mp.70008
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00