Evaluation of Cardiorenal Metabolic Syndrome in Patients with Heart Failure with Preserved Ejection Fraction. How Aware Are We?

Aim: Despite the prevalence of cardiorenal metabolic diseases (CRMD) in heart failure with preserved ejection fraction (HFpEF) patients and their significant complications, they are thought to be under-recognized and under-screened. In our study, we aimed to evaluate patients with HFpEF who were followed up in our internal medicine clinic. Methods: Our retrospective and cross-sectional study included 348 patients with HFpEF. Patients were evaluated according to laboratory, demographic, clinical, electrocardiographic and ultrasonographic findings. Results: Of the patients, 37.95% had diabetes mellitus, 23.3% had chronic kidney disease, 70.1% had hypertension and 59.2% had metabolic dysfunction-associated steatotic liver disease. The mean NT-proBNP level was 360.7 ± 13.7. Conclusion: We recommend that HFpEF, which is associated with increased cardiovascular mortality and morbidity in patients with CRMD, should be screened clinically and with NT-proBNP and evaluated with transthoracic echocardiography if necessary.

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Journal
Sakarya Medical Journal
Published
2025-09-09
DOI
https://doi.org/10.31832/smj.1684457
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Evaluation of Cardiorenal Metabolic Syndrome in Patients with Heart Failure with Preserved Ejection Fraction. How Aware Are We?

Hilmi Erdem Sümbül, Ahmet Gazi Mustan, Çiğdem Erhan, Erdinç Gülümsek et al.
Sakarya Medical Journal
Cardiovascular Function and Risk Factors
article

Evaluation of Cardiorenal Metabolic Syndrome in Patients with Heart Failure with Preserved Ejection Fraction. How Aware Are We?

Hilmi Erdem Sümbül, Ahmet Gazi Mustan, Çiğdem Erhan, Erdinç Gülümsek, Dilan Damla Öztürk, Berçem Berent Kaya, Tayyibe Saler, Fatih Necip Arıcı, Cisem Kizildag, Bektaş Işık, Uğur Can İzlimek, Hüseyin Ali Öztürk, Cahit Dincer, Mehmet Can Erişen
article en

Abstract

Aim: Despite the prevalence of cardiorenal metabolic diseases (CRMD) in heart failure with preserved ejection fraction (HFpEF) patients and their significant complications, they are thought to be under-recognized and under-screened. In our study, we aimed to evaluate patients with HFpEF who were followed up in our internal medicine clinic. Methods: Our retrospective and cross-sectional study included 348 patients with HFpEF. Patients were evaluated according to laboratory, demographic, clinical, electrocardiographic and ultrasonographic findings. Results: Of the patients, 37.95% had diabetes mellitus, 23.3% had chronic kidney disease, 70.1% had hypertension and 59.2% had metabolic dysfunction-associated steatotic liver disease. The mean NT-proBNP level was 360.7 ± 13.7. Conclusion: We recommend that HFpEF, which is associated with increased cardiovascular mortality and morbidity in patients with CRMD, should be screened clinically and with NT-proBNP and evaluated with transthoracic echocardiography if necessary.

Sakarya Medical JournalVol. 15(3)
Ergani Devlet Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Rize Devlet Hastanesi (TR)
Openalex Percentile: Top 60%
Cardiovascular Function and Risk Factors
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