Cyanostyryl‐Guanidiniocarbonyl‐Pyrrole Amphiphiles: From Aggregation‐Induced Emission to Photodimerization, Self‐Assembly, and Bioimaging
Two Cyanostyryl-guanidiniocarbonyl-pyrrole based amphiphiles are synthesized and examined in detail. In addition to achieving aggregation-induced emission from self-assembly, resulting in nanoparticles, it was found that the observed [2 + 2] photocycloaddition tunes the photophysical properties. The guanidiniocarbonyl-pyrrole component of these hybrid luminophores is shown to bind oxo-anions, such as pyrene-tetracarboxylate, as confirmed by fluorescence lifetime measurements. Moreover, both amphiphiles are used in bio-imaging experiments with HeLa cells, demonstrating effective cellular uptake.
Authors
- Nina Schulze
- Jens Voskuhl (ORCID: https://orcid.org/0000-0002-9612-2306)
- Thulaseedharan Nair Sailaja Sidharth (ORCID: https://orcid.org/0000-0001-7661-3231)
- Shirley K. Knauer (ORCID: https://orcid.org/0000-0003-4321-0924)
- Florian Uteschil (ORCID: https://orcid.org/0000-0003-4251-5988)
- Kevin Rudolph
- Elisabeth Verheggen
- Alexander Höing (ORCID: https://orcid.org/0000-0002-3762-4832)
- Felix C. Niemeyer (ORCID: https://orcid.org/0000-0002-9145-773X)
- Johannes Koch
- L. Hofmann (ORCID: https://orcid.org/0009-0002-2162-6494)
Institutions
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- ChemPlusChem
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1002/cplu.202500542
- Primary Topic
- Luminescence and Fluorescent Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Interdisciplinary Center for Analytics on the Nanoscale, University of Duisburg-Essen