Targeting CDK2 and CDK7: rational design of pyrazolo[1,5- <i>a</i> ]pyrimidine derivatives as potent anticancer agents

A series of novel pyrazolo[1,5- a ]pyramidal derivatives have been developed based on the structural analysis of previously identified CDK2 inhibitors.

Authors

Omneya M. El-Bakry
Marwa F. Harras (ORCID: https://orcid.org/0000-0003-4723-6179)
Ahmed B. M. Mehany
Mohamed M. Elsebaei (ORCID: https://orcid.org/0000-0002-0890-7219)
Hend M. El‐Sehrawi

Institutions

Al-Azhar University (EG)

Publication Details

Journal: New Journal of Chemistry
Published: 2025-01-01
DOI: https://doi.org/10.1039/d5nj02010g
Citations: 1
Primary Topic: Cancer-related Molecular Pathways
Type: article
Field-Weighted Citation Impact: 1.05

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article

Targeting CDK2 and CDK7: rational design of pyrazolo[1,5- a ]pyrimidine derivatives as potent anticancer agents

Omneya M. El-Bakry, Marwa F. Harras, Ahmed B. M. Mehany, Mohamed M. Elsebaei et al.

Jan 1, 2025

1 citations

New Journal of Chemistry

Cancer-related Molecular Pathways

1.05

article

Targeting CDK2 and CDK7: rational design of pyrazolo[1,5- a ]pyrimidine derivatives as potent anticancer agents

Omneya M. El-Bakry, Marwa F. Harras, Ahmed B. M. Mehany, Mohamed M. Elsebaei, Hend M. El‐Sehrawi

January 1, 2025article en

1 citations

Abstract

A series of novel pyrazolo[1,5- a ]pyramidal derivatives have been developed based on the structural analysis of previously identified CDK2 inhibitors.

New Journal of ChemistryVol. 49(40)

Al-Azhar University (EG)

Openalex Percentile: Top 17%

Cancer-related Molecular Pathways

1.05

DOI Source OpenAlex

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Targeting CDK2 and CDK7: rational design of pyrazolo[1,5- <i>a</i> ]pyrimidine derivatives as potent anticancer agents — Omneya M. El-Bakry, Marwa F. Harras, et al. · New Journal of Chemistry (2025) | TGRS Research Map | TGRS