Pre-irradiation administration of nilestriol promotes hematopoietic recovery but increases early mortality risk and impairs wound healing after total-body irradiation combined with wound trauma
These findings suggest that pre-irradiation administration of nilestriol can mitigate R-W-CI effects but requires careful consideration due to potential negative impacts on both systemic and local levels.
Authors
- Xiaofan Lv (ORCID: https://orcid.org/0000-0002-0085-9507)
- Jining Gao (ORCID: https://orcid.org/0000-0002-6435-4903)
- Na Zhao (ORCID: https://orcid.org/0000-0001-8648-9422)
- Guojian Wang (ORCID: https://orcid.org/0000-0001-5934-4594)
- Tao Wang (ORCID: https://orcid.org/0000-0003-0975-8072)
- Shuang Long
- Junping Wang (ORCID: https://orcid.org/0000-0001-5905-0940)
- Xinze Ran
Institutions
- Army Medical University (CN)
Publication Details
- Journal
- International Journal of Radiation Biology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1080/09553002.2025.2561816
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00