Polysaccharide from Trichosanthes kirilowii Maxim ameliorates diphenoxylate-induced functional constipation in mice
Collectively, these findings demonstrated that TKP could ameliorate diphenoxylate-induced functional constipation in mice, providing a pharmacological foundation for its development as a novel therapeutic agent against constipation.
Authors
- Guozhen Wu
- Min Jiang (ORCID: https://orcid.org/0000-0003-4935-315X)
- Wei Liu (ORCID: https://orcid.org/0000-0003-1811-9520)
- Tao Li (ORCID: https://orcid.org/0000-0002-0266-9846)
- Jiasheng Chen (ORCID: https://orcid.org/0000-0002-5115-032X)
- Xiao Wang (ORCID: https://orcid.org/0000-0002-1827-4427)
- C. Wang (ORCID: https://orcid.org/0009-0008-6946-7174)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Qilu University of Technology (CN)
- Jinan Central Hospital (CN)
- Shandong Academy of Sciences (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fmicb.2025.1672600
- Citations
- 1
- Primary Topic
- Microbial Metabolites in Food Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- Key Technology Research and Development Program of Shandong