Hypertoxic form of meningococcal infection: is it possible to save a child’s life? (Clinical case)

Meningococcal infection is characterized by an unpredictable course and a high mortality rate. Currently, doctors often have no previous experience of encountering and being wary of the disease. Missed opportunities due to late diagnosis and inadequate treatment significantly increase the likelihood of an unfavorable outcome. The objective of the study was to identify the most typical defects in providing medical care for generalized meningococcal infection based on the analysis of a clinical case of the disease in a young child. As a result of errors at the prehospital stage (ignorance of the peculiarities of the course of infection in children with a typical clinical picture, incorrect diagnosis, underestimation of the severity of the condition, transportation without monitoring vital signs and infusion support) and the initial stage in the hospital (delayed examination in the emergency room, lumbar puncture in the presence of contraindications, late initiation of respiratory support, incorrect tactics of anti-shock therapy), the chance for recovery could have been missed. The child developed critical complications (refractory septic shock, DIC syndrome, multiple organ failure), which led to a fatal outcome within the first day from the onset of the disease. The presented clinical case will help to increase the alertness of doctors to meningococcal infection and improve the quality of medical care. Following clinical recommendations will ensure adequate medical care at all stages, including the development of life-threatening conditions.

Authors

Institutions

Publication Details

Journal
Journal Infectology
Published
2025-09-22
DOI
https://doi.org/10.22625/2072-6732-2025-17-3-162-168
Primary Topic
Child and Adolescent Health
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Hypertoxic form of meningococcal infection: is it possible to save a child’s life? (Clinical case)

В. Н. Тимченко, Т. М. Chernova, D. O. Ivanov
Journal Infectology
Child and Adolescent Health
article

Hypertoxic form of meningococcal infection: is it possible to save a child’s life? (Clinical case)

В. Н. Тимченко, Т. М. Chernova, D. O. Ivanov
article en

Abstract

Meningococcal infection is characterized by an unpredictable course and a high mortality rate. Currently, doctors often have no previous experience of encountering and being wary of the disease. Missed opportunities due to late diagnosis and inadequate treatment significantly increase the likelihood of an unfavorable outcome. The objective of the study was to identify the most typical defects in providing medical care for generalized meningococcal infection based on the analysis of a clinical case of the disease in a young child. As a result of errors at the prehospital stage (ignorance of the peculiarities of the course of infection in children with a typical clinical picture, incorrect diagnosis, underestimation of the severity of the condition, transportation without monitoring vital signs and infusion support) and the initial stage in the hospital (delayed examination in the emergency room, lumbar puncture in the presence of contraindications, late initiation of respiratory support, incorrect tactics of anti-shock therapy), the chance for recovery could have been missed. The child developed critical complications (refractory septic shock, DIC syndrome, multiple organ failure), which led to a fatal outcome within the first day from the onset of the disease. The presented clinical case will help to increase the alertness of doctors to meningococcal infection and improve the quality of medical care. Following clinical recommendations will ensure adequate medical care at all stages, including the development of life-threatening conditions.

Journal InfectologyVol. 17(3)
Saint Petersburg State Pediatric Medical University (RU)
Openalex Percentile: Top 59%
Child and Adolescent Health
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.