Adverse events during radical prostatectomy and their association with recurrence and death
One/more adverse events occurred during 39% (1356/ 3444) of operations. Adverse events were associated with recurrence, but not with all-cause or prostate cancer specific mortality. Intraoperative extensive bleeding and difficulties during dissection were associated with recurrence. Risk factors included age at surgery, history of TUR-P or abdominal surgery, teaching, prostate weight and lymph node dissection. Limitations included the low number of observations (deaths), particularly in subgroup analyses and hospital volume. This study should be regarded as explorative. In this explorative study adverse events during radical prostatectomy were associated with increased risk for recurrence.
Authors
- Peter N. Wiklund (ORCID: https://orcid.org/0000-0001-6497-4697)
- Anders Bjartell (ORCID: https://orcid.org/0000-0002-5761-3786)
- Jonas Hugosson (ORCID: https://orcid.org/0000-0002-2324-2817)
- Anna Lantz (ORCID: https://orcid.org/0000-0002-5335-8028)
- Sofia Erestam (ORCID: https://orcid.org/0000-0002-3142-1903)
- Carolina Ehrencrona (ORCID: https://orcid.org/0000-0002-1460-1021)
- Eva Angenete (ORCID: https://orcid.org/0000-0001-9966-4904)
- Ying Li (ORCID: https://orcid.org/0000-0001-7108-6532)
- Eva Haglind
Institutions
- Mount Sinai Health System (US)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Skåne University Hospital (SE)
- University of Gothenburg (SE)
Publication Details
- Journal
- World Journal of Urology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1007/s00345-025-05932-7
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00