Dexmedetomidine as a Protective Agent Against X-Ray Ionizing Radiation-Induced Small Intestinal Injury
The findings suggest that DEX may effectively reduce X-ray-induced small intestinal injury in a dose-dependent manner, and that this effect is mediated through antioxidant and anti-apoptotic mechanisms. DEX holds potential for the prevention or treatment of radiation-induced gastrointestinal toxicities.
Authors
- Sema Yılmaz Rakıcı (ORCID: https://orcid.org/0000-0002-5543-9761)
- Levent Tümkaya (ORCID: https://orcid.org/0000-0001-5387-4666)
- Sibel Mataracı Karakas (ORCID: https://orcid.org/0000-0001-7147-5087)
- Süleyman Kalcan (ORCID: https://orcid.org/0000-0002-0829-7334)
- Ali Özdemir (ORCID: https://orcid.org/0000-0002-6435-1868)
- Gökhan Demiral (ORCID: https://orcid.org/0000-0003-2807-5437)
- Tolga Mercantepe (ORCID: https://orcid.org/0000-0002-8506-1755)
- Hamit Yılmaz (ORCID: https://orcid.org/0000-0002-8324-1891)
- Ahmet Pergel
Institutions
- Recep Tayyip Erdoğan University (TR)
- Ondokuz Mayıs University (TR)
- Kahramanmaraş Sütçü İmam University (TR)
Publication Details
- Journal
- Antioxidants
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3390/antiox14101153
- Citations
- 1
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Recep Tayyip Erdogan Üniversitesi